Hygrozyme Concentrate® is specifically designed with commercial growers in mind. Our formula has been created to be 5X concentrated allowing you to get more for less! Hygrozyme Concentrate® is one of the most competitively priced root enzyme-based formulas on the market, that provide a cleaner root zone! The new dosage application rate is 1.9 mL per 1 gallon of water, which means a 20 L / 5.28 gal bottle equals 100 L / 26.4 gal of our proven Hygrozyme® Original formula.

Provides a cleaner root zone
Accelerates breakdown of dead roots
Effective in all growing media & growth stages
Compatible with all nutrient & supplement programs
Supports Beneficial Microorganisms
Manufactured in a facility whose quality management is certified ISO 9001-2015

Hygrozyme Concentrate® Ingredients

Hygrozyme Concentrate contains the highly effective blend of enzymes as the original Hygrozyme that accelerates the breakdown of dead root matter. The enzymes in Hygrozyme Concentrate are specifically designed to work at their maximum strength in the pH and temperature range that is best suited for growing plants (in soil and hydroponics). It is important to have the right enzymes for the right purpose. To break down dead roots cellulase enzymes are needed, this is why we list our four main enzymes and their activity levels on our label.

Cellulase 5,000 U/mL
Xylanase 500 U/mL
Hemicellulase 375 U/mL
Beta-Glucanase 200 U/mL

Since enzymes are specific in the reactions they catalyze, a diverse variety of enzymes must be present in the root zone to carry out all the different biochemical transformations required to break down the various components of the decaying plant material.
To that effect, only when the right type of enzyme finds the right substrate, does a biochemical reaction occur. This specific interaction between an enzyme and a substrate means you don’t have to worry about undesirable effects. For instance, when cellulase breaks down cellulose, that’s all that will happen. No other material or process will be altered or affected. That’s why it is important to have a matching formula like Hygrozyme Concentrate, designed specifically to get rid of the bad without affecting the good.
To ensure full satisfaction and 100% guaranteed results, Hygrozyme Concentrate is manufactured in an ISO 9001:2015 certified production facility.

Hygrozyme Concentrate® Tissue Test

When choosing an enzyme product for plants, it is important to know if the enzyme formula contains the right enzymes to improve your indoor or outdoor grow system.

Tissue paper is essentially the same material as dead root matter (cellulose). The more the tissue paper breaks down, the higher the activity of the enzymes (cellulase enzyme) is in the product.

This simple test shows if the right enzymes are in the product to break down dead roots. Try the test at home by placing a sheet of tissue paper in a cup of enzyme product. Keep it at room temperature for 24 hours. Shake and observe to see if the tissue paper disintegrates.

Here is what you need to know to compare products


To protect consumers, many states including California and Oregon require enzyme products to list its active ingredients on the product label. Regulatory authorities ensure that the declared units of active ingredients are in fact present in the product. Check the ingredient list on the package and make sure that enzymes are actually listed by name. Enzyme names are easy to identify, as many enzyme names end in “ase” as an example active ingredients in Hygrozyme Concentrate are 5,000 U/mL cellulase, 500 U/mL xylanase, 375 U/mL hemicellulase and 200 U/mL beta-glucanase, which are also complimented by a unique blend of additional hydrolytic enzymes.

Products that break down dead root matter should be registered as an enzyme. If it’s registered as a fertilizer or not registered at all, it likely won’t help with keeping your roots clean.

If N-P-K is declared on the product label, then the product is likely registered as a fertilizer, not an enzyme. In this case, enzymes are not guaranteed as ingredients in the product.


Manufacturers can’t claim that the product “breaks down dead root matter” if the product isn’t registered as an enzyme formula. Additionally, they must declare the type of enzyme and level of activity to prove that the product does, in fact, break down dead organic matter.

Frequently Asked Questions

Enzymes are proteins, made up of amino acids that act as catalysts – they facilitate, energize, and speed up biochemical reactions. In fact, the rate of reaction can be several million times faster than if left un-catalyzed! An extreme example is orotidine 5′-phosphate decarboxylase, which allows a reaction that would otherwise take millions of years to occur in milliseconds.

Enzymes are not alive nor are they consumed when they catalyze a biochemical reaction. When the biochemical reaction is over, the enzyme is ready to bond to another substrate unit again. Given the right conditions, the enzyme can catalyze the same reaction time and time again.

Enzymes are used in various industries to make some of your favorite things like: tastier beer, softer cloths, better cheeses and juices, more efficient detergents etc.

Enzymes are highly specific. Only when the right enzyme finds the right substrate, does a biochemical reaction occur. This precise interaction means you never have to worry about undesirable effects. For instance, when cellulase breaks down cellulose into simple sugars, you can be sure that is all that will happen. No other material or process will be altered or affected. This is why it is important to have the right enzyme formula like Hygrozyme Concentrate designed specifically to get rid of the undesirable content without affecting the good.

Hygrozyme Concentrate’s pH is between 4 – 5 (variance because our enzymes are derived from natural sources)

Yes, you can use Hygrozyme Concentrate to flush your system. Mix 0.4 – 0.5 mL of Hygrozyme Concentrate per liter of water and flush your system. Stop using Hygrozyme Concentrate one week prior to harvest.

Depends on your nutrient or fertilizer program. We recommend using Hygrozyme Concentrate with every watering or nutrient change out. If you are adding beneficial microbials to your system, you have the option to add less beneficial microbials with every watering, as Hygrozyme Concentrate supports the growth of your beneficials.

You can use Hygrozyme Concentrate in all soil and soilless medias. We do not recommend the use of Hygrozyme Concentrate in Aquaponics systems.

Hygrozyme Concentrate is the most effective without hydrogen peroxide, therefore, we do not recommend using H2O2 with Hygrozyme Concentrate.

Yes, you can use beneficial microbials with Hygrozyme Concentrate. Hygrozyme Concentrate converts dead root matter into simple sugars which stimulate microbial growth (microbials consume simple sugars as carbon source for their growth.)

To preserve the shelf life and potency of the enzymes in Hygrozyme Concentrate, the best place to store Hygrozyme Concentrate is away from direct sunlight in a cool place. Keep below 90 °F /32°C for storage.

Hygrozyme Concentrate contains an industry leading concentration of 4 core enzymes: 5,000 U/mL Cellulase, 500 U/mL Xylanase, 375 U/mL Hemicellulase and 200 U/mL beta-Glucanase, which are also complemented by a unique blend of additional hydrolytic enzymes to assist in the effective breakdown of dead root matter.

Yes, it is recommended that you use Hygrozyme Concentrate with every growth stage. However, we recommended that you flush and only feed your plants water on the last week before harvest.

No, Hygrozyme Concentrate does not cure disease.

No, air pump will NOT cause enzyme shearing.

Yes. But since Hygrozyme Concentrate is a complete multi-enzyme blend, no additional enzymatic products are needed.

Hygrozyme Concentrate is compatible with all nutrient and supplement programs.

Yes, you can use Hygrozyme Concentrate past the 2-year shelf life however for best results, we recommend Hygrozyme Concentrate to be used within 2 years from the date of manufacture. Hygrozyme Concentrate is designed to retain the activity of its highly effective enzyme blend. SIPCO guarantees the enzyme activities in Hygrozyme Concentrate to be stable for two years, however if kept in appropriate storage conditions, the enzymes will still be active past the 2-year shelf life. If you plan to use Hygrozyme Concentrate beyond the 2-year shelf life, continue with recommended usage instructions on the product label. DO NOT increase dosage.

Enzymes, unlike any other catalyst, are highly substrate specific and hence do not cause undesirable effects.

No, you do not need to dilute Hygrozyme Concentrate. Be sure to you use Hygrozyme Concentrate at a much lower dosage application; 1.5 mL per 1 gallon of water.

A little truly goes a long way, we have heard growers demands to shipping less liquid and therefore Have developed a 5 X concentrated formula allowing for less shipping and covering 5 X more applications for the grower.

Want to start using Hygrozyme Concentrate? Find out how, all you have to do is Contact Us